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Figure 1 | Molecular Cancer

Figure 1

From: Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients

Figure 1

Increased phosphorylation of tuberin and decreased total tuberin in kidney tumors. Immunoblot analysis of phospho-tuberin (Thr 1462) and tuberin protein expression in normal kidney samples and tumor kidney from patients with tuberous sclerosis. Increased tuberin phosphorylation is associated with decreased total tuberin expression in tumor tissue compared to normal tissue. Tubulin was used as loading control. Histograms represent means ± SE normal kidney samples and kidney tumors from patients with tuberous sclerosis. Significant difference between control and tumor groups is indicated by **P < 0.01.

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