Figure 3
From: Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients
Downregulation of OGG1 mRNA is associated with decreased NF-YA protein expression in kidney tumors. Immunoblot analysis of NF-YA expression in normal kidney and kidney tumor from patients with tuberous sclerosis. Decreased OGG1 is associated with decreased NF-YA expression in tumor tissue compared to normal tissue. Tubulin was used as loading control. Histograms represent means ± SE normal kidney samples and tumors kidney from patients with tuberous sclerosis. Significant difference between control and tumor groups is indicated by **P < 0.01.