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Figure 6 | Molecular Cancer

Figure 6

From: Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

Figure 6

EF24 but not curcumin or DRB is more toxic to ATM-deficient mouse kidney cells than wild-type cells. A) 309ATM KO and 334ATM WT cells were treated with various concentrations of EF24. Cell viability was measured after 3 days by MTS assay. Each point represents the mean of 3 repeats. Error bars represent standard deviation. B) Similar experiment was performed using curcumin. C) Similar experiment was performed using DRB, a caseine kinase II inhibitor that does not inhibit the FA pathway in Xenopus extracts.

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