Effect of SAFB1 heterozygosity on Wnt-1-induced tumorigenesis. Kaplan-Meier survival curves of female (A) and male (B) SAFB1+/+/Wnt-1 and SAFB1+/-/Wnt-1 mice. Ages in weeks were recorded at the time of first tumor observation. C) and D) Growth rates of tumors in female and male Wnt-1 transgenic mice, respectively, on a SAFB1+/+ or SAFB1+/- background. The graphs represent time in weeks for tumor growth from detection to 1000 mm3, with error bars representing SEM.