Figure 4From: Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapyCorrelation between BLI and direct tumor volume determination in subcutaneous tumors. MC38Luc1 cells (106) were injected subcutaneously in the right hind flank of C57BL/6 mice (n = 14), and tumor progression was evaluated weekly by either BLI or direct measurement. A – Monitorization of tumor volume by direct measurement (calliper, black circles) corresponds to the left Y axis. Light emission quantified by BLI is represented as a dotted line and the scale corresponds to photons/s × 103 in the right Y axis. Error bars represent standard deviations. C-D – Correlation between light emission and direct tumor measurement 2 weeks (C) or 4 weeks (D) after cell implantation (log10 conversion of values).Back to article page