Skip to main content

Table 1 Different tools for molecular profiling at the genomic, transcriptomic, and protein levels

From: From bench to bedside: current and future applications of molecular profiling in renal cell carcinoma

Genomic

   • Comparative Genomic Hybridization (CGH)

   • Array-based CGH

   • Single Nucleotide Pleomorphism (SNP)

   • Multi-colour FISH

   • high-throughput sequencing techniques (hybridization-based, cycle-based, and single molecule based)

   • High-throughput analysis of methylation.

   • Spectral karyotyping (SKY)

Transcriptomic

   • Microarray

• mRNA

• microRNA

   • Serial Analysis of Gene Expression (SAGE)

   • Expressed Sequence Tags (EST)

   • Digital Differential Display (DDD)

   • Single Nucleotide Pleomorphism (SNP)

   • Quantitative RT-PCR

   • High throughout sequencing

   • In-situ hybridization

Proteomic

   • Mass spectrometry (different versions)

   • Protein microarray

   • Tissue microarray

   • Chromatography