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Table 1 Experimental design

From: Identification of novel Cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo

Week   -4 & -3 0 6 13 19
  Mice (n)      
Vehicle only
(V)
17 Mock infection Treatment begin 5 6 6
NS398 (10 mg/kg)
(NS398)
17 Mock infection Treatment begin 5 6 6
Vehicle plus H. pylori (V+ Hp) 24 Infect SS1 Treatment begin 8 8 8
NS398 (10 mg/kg) plus H. pylori
(NS398+Hp)
24 Infect SS1 Treatment begin 8 8 8
  1. After week 0 mice received daily sc. injections of NS398 or vehicle alone as indicated. Mice were killed at 6. 13 and 19 weeks after the start of treatment and H. pylori colonization (cfu), then pathology scores were determined and total RNA was prepared.