Figure 8From: siRNA-based targeting of antiapoptotic genes can reverse chemoresistance in P-glycoprotein expressing chondrosarcoma cellsClonogenic survival after siRNA and doxorubicin treatment. Clonogenic survival after chemotherapy and siRNA is shown. siRNA treatment with chemotherapy decreases colony formation by two times. Combinatorial siRNA treatments (Bcl-xl + PG or XIAP + PG siRNA) inhibited colony formation effectively after doxorubicin treatment. (PG: P-glycoprotein, *: p < 0.05).Back to article page