Figure 4From: CpG methylation profiling in VHL related and VHL unrelated renal cell carcinomaMost significant gene networks for genes more methylated in papillary RCC than clear cell RCC. Genes in unfilled nodes were not identified as specifically methylated in tumours (TGF-β, AKT, PDGFB) or were not represented on the array (ITGA8, ITGA10, ITGA11, PEBP4, ERK, SLC12A4, JNK, ITGB1BP2, CDO1, NCK1, NLK, PI3K, CNN2, FSD1, SLC7A8, ELOVL2, FXYD5, PDGFD and PDAP1. The computationally generated networks were derived using the Ingenuity package http://www.ingenuity.com. (see Figure 6 for key to nodal shape).Back to article page