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Table 2 Effect of long-term I2-treatment on mammary tumorigenesis after 16 weeks of MNU administration.

From: Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)

Treatment No. of rats with tumors % Tumor latency (weeks) Tumors per rat
MNU 10/10 100 11.9 ± 2.8 2.5 ± 1.7
I2-MNU 10/16* 62.5* 11.6 ± 1.4 2.0 ± 0.9
  1. At 5 weeks of age, rats were treated with 0.05% I2 in the drinking water. Two weeks later, rats received a single i.p. injection of MNU (50 mg/Kg bw), and the administration of I2 was continued until 16 weeks had elapsed. indicates mean ± SD. Asterisk (*) indicates P < 0.05 compared to MNU.