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Table 2 Effect of long-term I2-treatment on mammary tumorigenesis after 16 weeks of MNU administration.

From: Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR)

Treatment

No. of rats with tumors

%

Tumor latency (weeks)†

Tumors per rat†

MNU

10/10

100

11.9 ± 2.8

2.5 ± 1.7

I2-MNU

10/16*

62.5*

11.6 ± 1.4

2.0 ± 0.9

  1. At 5 weeks of age, rats were treated with 0.05% I2 in the drinking water. Two weeks later, rats received a single i.p. injection of MNU (50 mg/Kg bw), and the administration of I2 was continued until 16 weeks had elapsed. † indicates mean ± SD. Asterisk (*) indicates P < 0.05 compared to MNU.
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Molecular Cancer

ISSN: 1476-4598