TY - JOUR AU - Gill, Catherine AU - Dowling, Catherine AU - O'Neill, Amanda J. AU - Watson, R. William G. PY - 2009 DA - 2009/06/23 TI - Effects of cIAP-1, cIAP-2 and XIAP triple knockdown on prostate cancer cell susceptibility to apoptosis, cell survival and proliferation JO - Molecular Cancer SP - 39 VL - 8 IS - 1 AB - Manipulating apoptotic resistance represents an important strategy for the treatment of hormone refractory prostate cancer. We hypothesised that the Inhibitor of Apoptosis (IAP) Proteins may be mediating this resistance and knockdown of cIAP-1, cIAP-2 and XIAP would increase sensitivity to apoptosis. SN - 1476-4598 UR - https://doi.org/10.1186/1476-4598-8-39 DO - 10.1186/1476-4598-8-39 ID - Gill2009 ER -