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Figure 1 | Molecular Cancer

Figure 1

From: The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a

Figure 1

Identification of BRG1 as p16INK4a binding partner. A Schematic illustration of BRG1 highlighting the domains isolated in the yeast 2-hybrid screen (Y2H clone) B U2OS cells were transfected with MYC-p16INK4a and FLAG-BRG1 or control vector and immunoprecipitations were performed with a mouse-anti-FLAG antibody or a matched mouse IgG as indicated. BRG1 and p16INK4a were detected on immunoblots with anti-FLAG and anti-MYC antibodies. C Fluorescent microscopy images (FM) and confocal microscopy images (CF) of SW-13 cells grown on cover slips and transfected with MYC-p16INK4a and FLAG-BRG1 and probed with anti-FLAG and anti-MYC antibodies.

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