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Table 1 pRb pathway proteins in cell lines

From: The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a

  WMM1175-wtp16 U20S Saos-2 HCT116 H1299 C33A SW13
BRG1 + + + mutant - low -
BRM + + + + + - -
pRb + + - + + - +
CDK6 low + low low + - +
CDK4 + + + + + + +
p16 (-) - + - - + -
  1. Expression of the indicated proteins is summarized with + or -. Mutant status of BRG1 in HCT-116 cells has been reported [12].