Molecular Cancer

Table 1 pRb pathway proteins in cell lines

From: The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16^INK4a

	WMM1175-wtp16	U20S	Saos-2	HCT116	H1299	C33A	SW13
BRG1	+	+	+	mutant	-	low	-
BRM	+	+	+	+	+	-	-
pRb	+	+	-	+	+	-	+
CDK6	low	+	low	low	+	-	+
CDK4	+	+	+	+	+	+	+
p16	(-)	-	+	-	-	+	-

Expression of the indicated proteins is summarized with + or -. Mutant status of BRG1 in HCT-116 cells has been reported [12].

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ISSN: 1476-4598

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