Figure 3From: A universal assay for detection of oncogenic fusion transcripts by oligo microarray analysisFusion gene plots for four individual prostate cancer samples with the same fusion event. The four samples all had fusion transcripts with junctions between TMPRSS2 exon 1 and ERG exon 4. (A) Chimeric sequences plotted with increasing fusion scores. For the three first samples, the chimera of TMPRSS2:ERG exon1:4 had the highest ranking out of the 10,297 tested combinations. (B) Fusion map of each chimeric exon-exon junction of TMPRSS2 and ERG. Intensities of red indicate the relative values of the medians for the four replicate oligos for each chimeric exon-exon junction and the white arrows point to the correct fusion breakpoints. (C) Measurements from intragenic oligos (intra-exon probes) for ERG demonstrate a shift in intensities between exons three and four.Back to article page