Figure 1From: 14-3-3σ gene silencing during melanoma progression and its role in cell cycle control and cellular senescence14-3-3σ mRNA is downregulated in melanoma metastases compared with primary melanomas. Total mRNA was extracted from melanoma cells excised by laser-capture microdissection from primary melanomas (n = 11), lymph node (n = 10) and cutaneous metastases (n = 12), respectively. Quantitative real-time PCR was performed and relative mRNA expression levels are given as means +/- S.E.M. MM, primary melanomas; Meta (ln), lymph node metastases; Meta (s), cutaneous metastases.Back to article page