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Figure 1 | Molecular Cancer

Figure 1

From: Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus Latent Membrane Protein-1

Figure 1

Decreased SERCA3 expression in Burkitt's lymphoma cell lines infected with immortalization-competent Epstein-Barr virus. Panel A: Total cellular protein extracts from the BL-30 (lanes 1–3) and BL-41 (lanes 4–6) cell lines free of EBV (lanes 1,4) or chronically infected with the P3HR-1 (lanes 2,5) or the B95–8 (lanes 3,6) EBV strain were analysed by Western blotting for SERCA2 (top) and SERCA3 (center) expression in parallel with the detection of LMP-1 expression (bottom). Panels B,C,D,E: SERCA3 and SERCA2 expression in BL-30 (Panels B and C) and BL-41 cells (Panels D and E) infected with the P3HR-1 (grey columns) or the B95–8 (dark columns) EBV strains, respectively, expressed as % of SERCA expression in non-infected cells (white columns).

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