Figure 5

Immunohistochemical staining for SERCA3 protein in normal resting and activated B lymphocytes. SERCA expression in lymph node and mucosa associated lymphoid tissue was detected by imunohistochemistry using the PLIM430 monoclonal anti-SERCA3 antibody with o-diaminobenzidine as a chromogen and hematoxylin counterstain. Panel A: lymph node follicle Panel B: mantle zone small resting B lymphocytes (lower right) and germinal center activated lymphoblasts (upper left). Panel C: colonic intraepithelial lymphoid follicle with germinal center.