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Table 2 Univariate statistics Astro vs MB vs NB. Mean and standard error (SE) of metabolite levels for astrocytoma G1 (Astro) (N = 10), medulloblastoma (MB) (N = 9) and neuroblastoma (NB) (N = 7) tissue.

From: High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours

Metabolite Astro MB NB Two-tailed t-test (MB vs NB)
  Mean SE Mean SE Mean SE P value
NAA 0.90 0.29 0.66 0.22 1.26 0.48 -
Ace 0.19 0.06 0.09 0.03 0.17 0.06 -
Ala 1.63 0.51 1.48 0.49 1.25 0.47 -
Asp 0.54 0.17 0.22 0.07 0.32 0.12 -
Cho 0.52 0.17 0.68 0.23 0.81 0.30 -
Cr 2.45 0.77 2.05 0.68 0.96 0.36 < 0.01
Glu 2.57 0.81 2.90 0.97 3.50 1.32 -
Gln 5.36 1.69 3.15 1.05 0.61 0.23 < 0.001
GPC 0.81 0.25 0.60 0.20 0.61 0.23 -
Gly 1.57 0.50 2.83 0.94 1.29 0.49 < 0.05
Lac 13.5 4.27 9.29 3.10 11.2 4.24 -
m-Ins 2.25 0.71 1.72 0.57 2.72 1.03 -
PC 0.66 0.21 2.45 0.82 0.87 0.33 < 0.05
PEth 1.19 0.38 2.67 0.89 1.61 0.61 -
s-Ins 0.35 0.11 0.42 0.14 0.23 0.09 < 0.05
Suc 0.09 0.03 0.07 0.02 0.09 0.03 -
Tau 0.90 0.28 2.61 0.87 1.92 0.73 -
  1. Statistically significant differences between medulloblastomas and neuroblastomas resulting from two-tailed students t-tests assuming unequal variances are indicated. All metabolite quantities were divided by the fitted spectral area between 0.5 and 4.5 ppm. Tau – Taurine, Suc – Succinate, s-Ins – scyllo inositol, PEth – phosphorylethanolamine, PC – phosphorylcholine, m-Ins – myo-inositol, Lac – lactate, Gly – glycine, GPC – glycerophosphorylcholine, Gln – glutamine, Glu – glutamate, Cr – creatine, Cho – choline, Asp – aspartate, Ala – alanine, Ace – aspartate, NAA – N-acetylaspartate.