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Table 3 Thirty-seven differentially expressed genes between (SS) and (LS) of canine OS based on SAM analysis

From: Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times

Gene Clone ID

Q-value (%)

Fold change

Gene description

Gene symbol

DG2-21g13

0.00

4.1

WD repeat and SOCS box containing protein 2

WSB2

DG2-23c15

0.00

3.3

cofilin 2

CFL2

DG2-72g4

0.00

2.7

ankyrin repeat domain protein 17 isoform a

ANKRD17

DG42-128j23

0.00

2.1

paraoxonase 1

PON1

DG2-112n11

0.00

2.1

Kinesin heavy chain (Ubiquitous kinesin heavy chain)

UKHC

DG32-161c11

0.00

2.0

WNK lysine deficient protein kinase 1

WNK1

DG2-63l7

0.00

1.7

nuclear receptor co-repressor 1

NCOR1

DG32-237k11

0.00

1.6

Ribosomal L1 domain containing protein 1(PBK1)

RSL1D1

DG11-239n21

0.00

1.6

cell-cycle and apoptosis regulatory protein 1

CCAR1

DG2-28n13

0.00

1.5

28S ribosomal protein S31, mitochondrial precursor

MRPS31

DG2-59p21

0.00

1.4

#NA

 

DG2-90b10

4.61

2.2

Heat shock protein HSP 90-alpha

HSP90

DG2-123a3

4.61

2.0

Microsomal glutathione S-transferase 1

MGST1

DG2-86b3

4.61

1.6

Canis familiaris similar to T06D8.1a

 

DG8-102i3

4.61

1.5

#NA

 

DG2-100e22

4.61

1.5

COMM domain containing protein 8

COMMD8

DG2-106f2

4.61

1.4

Translocation protein SEC63 homolog

SEC63

DG2-130m14

4.61

1.4

Canis familiaris similar to CG1218-PA

 

DG2-90c16

6.15

2.6

#NA

 

DG43-1a15

6.15

2.4

#NA

 

DG14-71c7

6.15

1.8

serine/arginine repetitive matrix 1

SRRM1

DG2-72p3

6.15

1.6

Vacuolar ATP synthase subunit C

V-ATPase C

DG32-216j13

6.15

1.6

Flavin reductase (NADPH-dependent diaphorase) (FLR)

BVRB

DG2-94j4

6.15

1.5

Canis lupus familiaris high-mobility group box 1

HMGB1

DG2-42j4

6.15

1.4

FRA10AC1 protein isoform FRA10AC1-1)

 

DG42-89n19

6.15

1.4

#NA

 

DG2-19i16

9.70

7.2

#NA

 

DG2-18m22

9.70

4.6

plasma glutamate carboxypeptidase

PGCP

DG9-134g22

9.70

1.9

ankyrin repeat domain 11

ANKRD11

DG2-123m9

9.70

1.9

CG12795-PA

 

DG14-14i19

9.70

1.7

Stress-70 protein, mitochondrial precursor (HSAP9) (Mortalin)

MOT

DG9-212f9

9.70

1.5

CG12795-PA

 

DG2-60f11

9.70

1.5

#NA

 

DG2-25k5

9.70

1.4

SMC6 protein

SMC6

DG14-86l17

9.70

1.4

#NA

 

DG2-24i24

9.70

1.4

60 kDa heat shock protein, mitochondrial precursor

HSP60

DG11-243e16

9.70

1.4

splicing factor, arginine/serine-rich 2, interacting protein

SFRS2IP

  1. All these genes were upregulated in short survivors. Genes were selected at a FDR <10% and of fold change of ≥1.4. (*#NA: non-annotated for Canis familiaris)