Skip to main content

Table 4 Gene transcripts overexpressed in short survivors of canine OS found associated with 3 main biological processes

From: Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times

Gene ID

Fold change

Gene description

Gene symbol

Metastasis-associated

DG2-23c15

3.3

cofilin 2

CFL2

DG14-14i19

1.7

Stress-70 protein, mitochondrial precursor (HSAP9) (GRP 75) (Mortalin)

MOT

DG2-72p3

1.6

Vacuolar ATP synthase subunit C

V-ATPase C

Drug resistance

DG2-112n11

2.1

Kinesin heavy chain (Ubiquitous kinesin heavy chain)

UKHC

DG2-123a3

2.0

Microsomal glutathione S-transferase 1

MGST1

DG2-72p3

1.6

Vacuolar ATP synthase subunit C

V-ATPase C

DG2-94j4

1.5

high-mobility group box 1

HMGB1

Cell cycle/proliferation

DG2-23c15

3.3

cofilin 2

CFL2

DG32-161c11

2.0

WNK lysine deficient protein kinase 1

WNK1

DG14-71c7

1.8

serine/arginine repetitive matrix 1

SRRM1

DG14-14i19

1.7

Stress-70 protein, mitochondrial precursor (HSAP9) (GRP 75) (Mortalin)

MOT

DG32-237k11

1.6

Ribosomal L1 domain containing protein 1(PBK1 protein)

RSL1D1

DG11-239n21

1.6

cell-cycle and apoptosis regulatory protein 1

CCAR1

DG2-106f2

1.4

Translocation protein SEC63 homolog

SEC63

DG2-25k5

1.4

SMC6 protein

SMC6

  1. The 3 processes commonly confer for the aggressive phenotype of tumor in general which include increased drug resistance, high proliferation and differentiation and high metastasis.
Back to article page

Molecular Cancer

ISSN: 1476-4598