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Table 1 Sequence variants detected in a NSCLC FFPE sample, TX49, by LCN-HRM.

From: Limited copy number - high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies

Sample

Position

Base change

Amino acid change

Reported

TX49

c.2488

G>A

p.D830N

No

 

c.2488

G>A

p.D830N

No

 

c.2499

G>A

p.L833L

No

 

c.2502

G>A

p.V834V

No

 

c.2506

C>T

p.R836C

Yes

 

c.2507

G>T

p.R836L

No

 

c.2519

C>T

p.A840V

No

 

c.2526

C>T

p.N842N

No

 

c.2577

C>T

p.A859A

No

 

c.2581

C>T

p.L861L

No

 

c.2593

G>A

p.E865K

Yes

 

c.2603

A>G

p.E868G

Yes

 

c.2625+1

G>A

-

No