Table 2 The sequence variants detected in TX86 by LCN-HRM using three different DNA polymerases.

c.2515

G>T

p.A839S

No

c.2519

C>T

p.A840V

No

c.2527

G>A

p.V842I

Yes

c.2532

G>A

p.L844L

No

c.2583

G>A

p.L861L

No

c.2588

G>A

p.G863D

Yes

c.2592

G>A

p.A864A

No

c.2602

G>A

p.E868K

No

c.2494

C>T

p.R832C

No

c.2512

C>T

p.L838L

No

c.2570

G>T

p.G857V

No

c.2576

C>T

p.A859V

No

c.2478

C>A

p.N826K

No

c.2484

G>T

p.L828F

No

c.2488

G>T

p.D830Y

No

c.2492

G>A

p.R831H

Yes

c.2494

C>T

p.R832C

No

c.2508

C>A

p.R836R

SNP

c.2508_2509

CG>TA

p.R836R, p.D837N

No

c.2509

G>T

p.D837Y

No

c.2515

G>A

p.A839T

Yes

c.2517

A>G

p.A839A

No

c.2522

G>T

p.R841M

No

c.2530

C>A

p.L844M

No

c.2543

C>A

p.P848Q

No

c.2581

C>A

p.L861M

No

c.2591

C>T

p.A864V

No

c.2607

C>A

p.Y869X

No

c.2622

C>A

p.G874G

No