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Figure 6 | Molecular Cancer

Figure 6

From: Hypomethylation and expression of BEX2, IGSF4 and TIMP3 indicative of MLL translocations in Acute Myeloid Leukemia

Figure 6

MLL fusion proteins regulate Bex2 expression. In presence of 4-OHT (100 nM) MLL-ENL-ERtm mouse cell lines expressed MLL-ENL and Bex2. Withdrawal of 4-OHT for seven to nine days induced downregulation of MLL-ENL and suppression of Bex2 transcription. Bex2 expression levels with standard deviations were determined in two different MLL-ENL-ERtm cell line clones by quantitative real-time PCR analysis.

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