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Figure 4 | Molecular Cancer

Figure 4

From: Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness

Figure 4

Adhesion of MCF-10A neoT cells to fibronectin in the presence of anti-CK MAb and uPA. MCF10A neoT cells were cultured on a fibronectin coated surface in the absence or presence of anti-CK MAb and/or uPA. The percentage of adherent cells was assessed with MTS assay. The time course of adhesion to the fibronectin surface is shown (See also Video S1 and S2). Samples were analyzed in quadruplicate and each point is the mean of at least three independent experiments.

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