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Figure 5 | Molecular Cancer

Figure 5

From: Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness

Figure 5

Anti-CK MAb changes the morphology of MCF-10A neoT cells cultured on fibronectin. Photomicrographs of MCF-10A neoT cells cultured for 24 h on uncoated (below) or fibronectin-coated surfaces (above) are shown for control and anti-CK8 MAb treated cells. Anti-CK MAb enables the adhesion to fibronectin of MCF-10A neoT cells, but not control cells, which form cell clusters. In contrast, both control and anti-CK MAb treated cells adhere to uncoated surface.

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