Table 4 Differentially expressed genes common for TUSC2-expressing MPM cells and clinical tumor specimens.
From: Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects
| Â | Fold change and direction in TUSC2-transfected MPM cells versus control | Fold change and direction in MPM versus healthy peritoneum | Gene product name | Gene ID |
|---|---|---|---|---|
1 | -8.04 | 1.90 | ribosomal protein S11 | RPS11 |
2 | -4.51 | 3.50 | histone cluster 1, H2ae | HIST1H2AE |
3 | -4.10 | 3.50 | regulator of G-protein signaling 4 | RGS4 |
4 | -3.90 | 1.80 | parathyroid hormone-like hormone | PTHLH |
5 | -3.64 | 7.00 | histone cluster 1, H2bg | HIST1H2BG |
6 | -3.14 | 2.50 | CD24 molecule | CD24 |
7 | -3.08 | 1.40 | proteasome (macropain) subunit, beta type, 4 | PSMB4 |
8 | -2.92 | 4.80 | lysyl oxidase | LOX |
9 | -2.31 | 2.50 | protein phosphatase 1, regulatory subunit 15A | PPP1R15A |
10 | -2.59 | 2.90 | histone cluster 1, H4 h | HIST1H4H |
11 | -2.67 | 2.87 | activating transcription factor 3 | ATF3 |
12 | -2.26 | 1.40 | SET translocation (myeloid leukemia-associated) | SET |
13 | -2.22 | 1.30 | histone cluster 2, H2be | HIST2H2BE |
14 | -2.22 | 4.87 | hypothetical protein LOC284801 | LOC284801 |
15 | -2.21 | 2.51 | transmembrane protein 158 | TMEM158 |
16 | -2.18 | 1.50 | histone cluster 2, H2aa3 | HIST2H2AA3 |
17 | -2.14 | 3.75 | F-box protein 32 | FBXO32 |
18 | -2.12 | 2.10 | histone cluster 1, H3d | HIST1H3D |
19 | -2.12 | 2.73 | SRY (sex determining region Y)-box 4 | SOX4 |
20 | -2.04 | 1.48 | fem-1 homolog b (C. elegans) | FEM1B |
21 | 2.02 | -1.35 | BCL2-like 11 (apoptosis facilitator) | BCL2L11 |
22 | 2.02 | -2.10 | WD repeat and SOCS box-containing 1 | WSB1 |
23 | 2.03 | -2.96 | chromosome 1 open reading frame 21 | C1orf21 |
24 | 2.04 | -1.30 | muscleblind-like (Drosophila) | MBNL1 |
25 | 2.10 | -2.20 | selenium binding protein 1 | SELENBP1 |
26 | 2.12 | -1.28 | butyrophilin, subfamily 3, member A1 | BTN3A1 |
27 | 2.13 | -2.20 | AF4/FMR2 family, member 4 | AFF4 |
28 | 2.18 | -1.98 | transmembrane protein 47 | TMEM47 |
29 | 2.24 | -2.52 | superoxide dismutase 2, mitochondrial | SOD2 |
30 | 2.30 | -2.20 | SID1 transmembrane family, member 2 | SIDT2 |
31 | 2.35 | -1.82 | transmembrane and coiled-coil domain family 1 | TMCC1 |
32 | 2.36 | -2.52 | early growth response 1 | EGR1 |
33 | 2.40 | -2.90 | aldehyde dehydrogenase 6 family, member A1 | ALDH6A1 |
34 | 2.44 | -1.50 | cyclin G2 | CCNG2 |
35 | 2.50 | -1.54 | cell division cycle 2-like 6 (CDK8-like) | CDC2L6 |
36 | 2.52 | -5.20 | ribonuclease, RNase A family, 4 | RNASE4 |
37 | 2.53 | -3.80 | tensin 1 | TNS1 |
38 | 2.54 | -1.80 | myeloid/lymphoid or mixed-lineage leukemia 5 | MLL5 |
39 | 2.57 | -2.20 | forkhead box N3 | FOXN3 |
40 | 2.75 | -3.32 | zinc finger E-box binding homeobox 1 | ZEB1 |
41 | 2.76 | -2.30 | protocadherin 17 | PCDH17 |
42 | 3.06 | -9.20 | cytochrome P450, family 4, subfamily F | CYP4F3 |
43 | 3.18 | -1.36 | complement component 3 | C3 |
44 | 3.30 | -2.03 | AT rich interactive domain 5B (MRF1-like) | ARID5B |