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Table 4 Differentially expressed genes common for TUSC2-expressing MPM cells and clinical tumor specimens.

From: Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects

  Fold change and direction in TUSC2-transfected MPM cells versus control Fold change and direction in MPM versus healthy peritoneum Gene product name Gene ID
1 -8.04 1.90 ribosomal protein S11 RPS11
2 -4.51 3.50 histone cluster 1, H2ae HIST1H2AE
3 -4.10 3.50 regulator of G-protein signaling 4 RGS4
4 -3.90 1.80 parathyroid hormone-like hormone PTHLH
5 -3.64 7.00 histone cluster 1, H2bg HIST1H2BG
6 -3.14 2.50 CD24 molecule CD24
7 -3.08 1.40 proteasome (macropain) subunit, beta type, 4 PSMB4
8 -2.92 4.80 lysyl oxidase LOX
9 -2.31 2.50 protein phosphatase 1, regulatory subunit 15A PPP1R15A
10 -2.59 2.90 histone cluster 1, H4 h HIST1H4H
11 -2.67 2.87 activating transcription factor 3 ATF3
12 -2.26 1.40 SET translocation (myeloid leukemia-associated) SET
13 -2.22 1.30 histone cluster 2, H2be HIST2H2BE
14 -2.22 4.87 hypothetical protein LOC284801 LOC284801
15 -2.21 2.51 transmembrane protein 158 TMEM158
16 -2.18 1.50 histone cluster 2, H2aa3 HIST2H2AA3
17 -2.14 3.75 F-box protein 32 FBXO32
18 -2.12 2.10 histone cluster 1, H3d HIST1H3D
19 -2.12 2.73 SRY (sex determining region Y)-box 4 SOX4
20 -2.04 1.48 fem-1 homolog b (C. elegans) FEM1B
21 2.02 -1.35 BCL2-like 11 (apoptosis facilitator) BCL2L11
22 2.02 -2.10 WD repeat and SOCS box-containing 1 WSB1
23 2.03 -2.96 chromosome 1 open reading frame 21 C1orf21
24 2.04 -1.30 muscleblind-like (Drosophila) MBNL1
25 2.10 -2.20 selenium binding protein 1 SELENBP1
26 2.12 -1.28 butyrophilin, subfamily 3, member A1 BTN3A1
27 2.13 -2.20 AF4/FMR2 family, member 4 AFF4
28 2.18 -1.98 transmembrane protein 47 TMEM47
29 2.24 -2.52 superoxide dismutase 2, mitochondrial SOD2
30 2.30 -2.20 SID1 transmembrane family, member 2 SIDT2
31 2.35 -1.82 transmembrane and coiled-coil domain family 1 TMCC1
32 2.36 -2.52 early growth response 1 EGR1
33 2.40 -2.90 aldehyde dehydrogenase 6 family, member A1 ALDH6A1
34 2.44 -1.50 cyclin G2 CCNG2
35 2.50 -1.54 cell division cycle 2-like 6 (CDK8-like) CDC2L6
36 2.52 -5.20 ribonuclease, RNase A family, 4 RNASE4
37 2.53 -3.80 tensin 1 TNS1
38 2.54 -1.80 myeloid/lymphoid or mixed-lineage leukemia 5 MLL5
39 2.57 -2.20 forkhead box N3 FOXN3
40 2.75 -3.32 zinc finger E-box binding homeobox 1 ZEB1
41 2.76 -2.30 protocadherin 17 PCDH17
42 3.06 -9.20 cytochrome P450, family 4, subfamily F CYP4F3
43 3.18 -1.36 complement component 3 C3
44 3.30 -2.03 AT rich interactive domain 5B (MRF1-like) ARID5B
  1. Comparison between expression array data sets reveals 44 concordantly regulated gene