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Figure 1 | Molecular Cancer

Figure 1

From: Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival

Figure 1

Aur-A is overexpressed in TSCC tissues and correlated with clinical stage and lymph node metastasis. TSCC or its corresponding adjacent normal samples were collected and subjected to immunohistochemical staining with Aur-A antibody. (a) Aur-A expression is low in normal samples. (b) Aur-A expression is obviously increased in TSCC, original magnification, × 200. Insets show enlarged views, original magnification, × 400.

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