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Figure 4 | Molecular Cancer

Figure 4

From: Aurora-A down-regulates IkappaBα via Akt activation and interacts with insulin-like growth factor-1 induced phosphatidylinositol 3-kinase pathway for cancer cell survival

Figure 4

Aur-A interacts with PI3K pathway in regulating TSCC cell migration. Cells were incubated in serum-free media containing IGF-1 (I, 100 ng/ml), wortmannin (W, 1 μM), VX-680 (V, 1 nM) alone or in combination for 16 h. Migration rates were quantified by counting the migrated cells in five random fields. (a) One representative of three independent experiments was shown, original magnification × 200. (b) Data summarized three independent experiments in identical condition.

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