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Figure 3 | Molecular Cancer

Figure 3

From: Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro

Figure 3

Effect of IGFBP3 overexpression on GIST-T1 cell viability. (A) Whole cell lysates isolated from GIST-T1 cells three or five days after mock infection or infection with indicated titers (moi) of adenovirus expressing IGFBP3 (Ad-IGFBP3) or empty vector (Ad-EV) were analyzed by immunoblotting for IGFBP3 expression. Viability of GIST-T1 cells mock infected or infected with indicated titers of Ad-EV or Ad-IGFBP3 was analyzed 3 days (B) or 5 days (C) post-infection with the MTS assay. Asterisks (*) denote significant differences in cell viability at the indicated doses of Ad-EV vs. Ad-IGFBP3.

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Molecular Cancer

ISSN: 1476-4598