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Figure 8 | Molecular Cancer

Figure 8

From: Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

Figure 8

EBNA1 inhibits the phosphorylation of IκBα and IKKα/β in carcinoma cells. (A) Western blot analysis of total and phosphorylated IκBα (ser32) in Ad/AH and Hone1 cells stably expressing EBNA1 or a neomycin control vector (neo).(B) Western blot analysis of total IKKα, IKKβ, IKKγ and phosphorylated IKKα/β (IKKα Ser176/180 and IKKβ Ser177/181) in Ad/AH and Hone1 cells stably expressing EBNA1 or a neomycin control vector (neo). Western blotting for EBNA1 and β-actin serve as EBNA1 expression and protein loading controls, respectively.

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Molecular Cancer

ISSN: 1476-4598