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Table 3 Genes/Probe IDs showing statistically significant different DNA copy number and mRNA expression in early versus late onset colorectal cancers.

From: Distinct high resolution genome profiles of early onset and late onset colorectal cancer integrated with gene expression data identify candidate susceptibility loci

     

Patients with chromosomal aberrations

Copy number aberration

Gene/Probe ID

Chromosome band

Mbps§ from pter

Size# (Kbps)

Early onset (n = 23)

Late onset (n = 17)

Gain

CLC/118354

19q13.2

44.9

6.8

7

0

 

LTBP4/162965

19q13.2

45.8

30.6

6

0

 

ZNF574/130858

19q13.2

47.3

11.2

6

0

Loss

PPAT/156570

4q12

57.1

42.3

12

3

 

EIF4E/195966

4q23

100.2

22.1

12

3

 

RG9MTD2/125412

4q23

100.8

16.9

12

3

 

PLA2G12A/106464

4q25

111.0

16.5

12

3

  1. §Gene start position, indicated as Mbps from pter
  2. #Gene size, indicated in Kbps