Table 4 Genes coding for molecules controlling adhesion and movement displaying altered expression in LP-1 derivatives (|FC|>3).
From: Cyclin K and cyclin D1b are oncogenic in myeloma cells
Gene | Protein | LP-1D1b vs. cl1 | LP-1K vs. cl1 |
|---|---|---|---|
CX3CR1 | Chemokine (C-X-C motif) receptor 1 | nm* | +63.24** |
CD99 | CD99 molecule | nm | +52.47 |
FXYD5 | FXY domain containing ion transport regulator 5 | nm | +43.74 |
CD9 | CD9 molecule | nm | +35.80 |
SPON1 | Spondin 1 | nm | +21.37 |
CD4 | CD4 molecule | nm | +18.57 |
CXCL12 | Chemokine (C-X-C motif) ligand 12 | nm | +17.26 |
ARGDIB | RhoGDP dissociation inhibitor (GDI) beta | nm | +13.55 |
FN1 | Fibronectin 1 | nm | +13.54 |
SUT3 | SUT homolog 3 | nm | +13.44 |
ICAM3 | Intracellular adhesion molecule 3 | nm | +13.34 |
LAMB3 | Laminin beta 3 | nm | +12.74 |
PCDH1 | Protocadherin 1 | nm | +12.05 |
CNTNAP2 | Contactin associated protein-like 2 | nm | +11.79 |
MCAM | Melanoma cell adhesion molecule | nm | +10.70 |
CCL2 | Chemokine (C-C motif) ligand 2 | nm | +10.09 |
SYK | Spleen tyrosine kinase | nm | +9.87 |
ANXA9 | Annexin A9 | nm | +9.33 |
LAMA3 | Laminin alpha 3 | nm | +8.46 |
LPXN | Leupaxin | nm | +7.86 |
CD93 | CD93 molecule | nm | +7.60 |
ERBB2IP | Erbb2 interacting protein | nm | +6.12 |
NRCAM | Neuronal cell adhesion molecule | nm | +6.09 |
ITGB2 | Integrin beta 2 | nm | +6.08 |
PCDH1 | Protocadherin 1 | nm | +5.77 |
CD97 | CD97 molecule | nm | +5.38 |
ADAM23 | ADAM metallopeptidase domain 23 | nm | +4.90 |
CTGF | Connective tissue growth factor | nm | +4.60 |
CD36 | CD36 molecule | nm | +4.53 |
NLGN1 | Neuroligin | nm | +4.50 |
CD44 | CD 44 molecule | nm | +4.21 |
CNTNAP2 | Contactin associated protein-like 2 | nm | +4.03 |
CD33 | CD33 molecule | nm | +4.02 |
HNT | Neurtrimin | nm | +3.97 |
SELPLG | Selectin P ligand | nm | +3.92 |
PKD2 | Polycystic kidney disease | nm | +3.80 |
SIGLEC7 | Sialic acid binding Ig-like lectin 7 | nm | +3.56 |
L1CAM | L1 cell adhesion molecule | nm | +3.21 |
COL18A1 | Collagen type XVIII alpha 1 | nm | +3.20 |
ADAM15 | ADAM metallopeptidase domain 15 | nm | +3.18 |
CDSN | Corneodesmosin | nm | +3.17 |
SIGLEC9 | Sialic acid binding Ig-like lectin 9 | nm | +3.11 |
NEO1 | Neogenin homolog 1 | nm | -3.22 |
TROAP | Trophilin-associated protein | nm | -3.60 |
ITGA6 | Integrin alpha 6 | nm | -3.86 |
ITGAE | Integrin alpha E | nm | -3.96 |
DST | Distonin | nm | -4.00 |
COL24A1 | Collagen type XXIV alpha 1 | nm | -4.07 |
JAM3 | Junctional adhesion molecule 3 | nm | -4.26 |
PKP2 | Plakophilin 2 | nm | -5.11 |
SPN | Sialophorin (CD43) | nm | -5.55 |
JAM2 | Junctional adhesion molecule 2 | nm | -12.09 |
ITGB7 | Integrin beta7 | -4.26 | +4.65 |