Functional groups* Gene name | Accession #† | Gene‡ | Locus | In vitro | In vivo |
---|---|---|---|---|---|
Angiogenesis/hypoxia | |||||
CD36 antigen (TSP1 receptor) | NM_001001547 | CD36 | 948 | + | |
Vascular endothelial growth factor | NM_001025366 | VEGF | 7442 | - | |
Thrombospondin 1 (THBS1, TSP1) | NM_003246 | THBS1 | 7057 | + | +** |
Endothelial PAS domain protein 1 | NM_001430 | EPAS1 | 2034 | + | |
Neuropilin 2 | NM_003872 | NRP2 | 8828 | + | |
Stabilin1 | NM_015136 | STAB1 | 23166 | + | |
Angiopoietin 2 | NM_001147 | ANGPT2 | 285 | - | - |
Cadherin 13 | NM_001257 | CDH13 | 1012 | + | |
Hypoxia-inducible protein 2 | NM_013332 | HIG2 | 29932 | - | |
Cell cycle/differentiation/senescence/apoptosis | |||||
Cyclin-depenent inhibitor kinase 1C | NM_000076 | CDKN1C | 1028 | - | |
Adrenomedullin | NM_001124 | ADM | 133 | - | |
Fibroblast growth factor | NM_033136 | FGF1 | 2246 | + | |
Advanced Glycosylation Endproduct Recept | NM_001136 | AGER | 177 | - | |
Leukocyte specific transcript protein 1 | NM_007161 | LST1 | 7941 | + | |
Forkhead box protein N4. | NM_213596 | FOXN4 | 121643 | + | |
Jun D proto-oncogene; AP-1 complex | NM_005354 | JUND | 3727 | - | |
Invasion/migration/adhesion/metastasis | |||||
Lysyloxidase preprotein | NM_002317 | LOX | 4015 | - | - |
Secreted phosphoprotein | NM_00582 | SPP1 | 6996 | - | |
Chemokine (C-X-C motif) receptor 4 | NM_003467 | CXCR4 | 7852 | - | |
Spleen tyrosine kinase | NM_003177 | SYK | 6850 | + | |
Vimentin | NM_003380 | VIM | 7431 | + | |
CD44 antigen isoform a | NM_000610 | CD44 | 960 | + | |
CD74 antigen | NM_004355 | CD74 | 972 | + | |
Insulin-like growth factor binding prot 3 | NM_000598 | IGFBP3 | 3486 | - | |
S100 calcium-binding protein A6 | NM_014624 | S100A6 | 6277 | + | |
S100 calcium binding protein P | NM_005980 | S100P | 6286 | + | |
P8 protein (candidate of metastasis 1) | NM_012385 | NUPR1 | 26471 | - | |
Matrix metalloproteinase 14 | NM_004995 | MMP14 | 4323 | + | |
Latent transforming GFB-binding prot | NM_032035 | LTBP2 | 4053 | + | |
Insulin-like growth factor binding prot 7 | NM_001553 | IGFBP7 | 3490 | + | |
Stress response/metabolism/DNA repair | |||||
cytochrome P450, family 1, subfamily A | NM_000499 | CYP1A1 | 1543 | + | + |
cytochrome P450, family 1, subfamily A | NM_000761 | CYP1A2 | 1544 | + | |
growth differentiation factor 15 (NAG1) | NM_004864 | GDF15 | 9518 | + | |
DNA-damage-ind. transcript 3 (GADD153) | NM_004083 | DDIT3 | 1649 | + | - |
TCDD-inducible poly(ADP-ribose) polymerase | NM_015508 | TIPARP | 25976 | + | + |
Tumor protein p53 inducible nulear prot 2 | NM_021202 | TP53INP2 | 58476 | + | |
Inflammatory response | |||||
Myeloperoxidase | NM_000250 | MPO | 4353 | - | |
Interleukin 8 receptor beta | NM_001557 | IL8RB | 3579 | - | |
Interleukin 12 alpha chain | NM_000882 | IL12A | 3592 | - | |
Serpin peptidase inhibitor 1 | NM_001085 | SERPINA3 | 12 | - |