Figure 8
From: MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
csMUC16 shields ovarian cancer cells from NKL mediated lysis. A. NKL cells were added to confluent cultures of csMUC16neg-OVC or csMUC16pos-OVC cells at a 1:1 effector:target ratio. After incubation for A, 24 h and B, 48 h the number of adherent colonies and adherent cells surviving the NKL challenge were counted by microscopic examination of five random fields. This experiment was repeated in triplicate and mean values (n = 15 fields) and standard deviation are shown.