Figure 9
From: MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells
Tumor cells surviving NKL challenge express higher levels of csMUC16. A. csMUC16pos-OVC cells not treated with NKL or those surviving NKL treatment (csMUC16pos-OVC-R) were analyzed for csMUC16 expression by flow cytometry. Data is representative of three independent experiments. B, csMUC16pos-OVC and csMUC16pos-OVC-R were labeled with 51Cr. Cytotoxity assays were performed by using NKL cells as effectors. After 4 h co-incubation, released radioactivity was measured. Each bar is mean of four independent assays.