Figure 6From: Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-AblEffect of pristimerin on cell cycling in CML cells. KBM5, KBM5-T315I or K562 cells were treated with pristimerin at the indicated concentrations for 24 hours, cell cycling was analyzed by flow cytometry after staining with propidium iodide. Graphs show data from a representative experiment.Back to article page