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Figure 5 | Molecular Cancer

Figure 5

From: Sensitization of cervix cancer cells to Adriamycin by Pentoxifylline induces an increase in apoptosis and decrease senescence

Figure 5

Determination of SA-β-gal associated senescence of HeLa, SiHa and HaCaT cells after in vitro treatment with Pentoxifylline (PTX) or Adriamycin (ADR) either alone or in combination. Cell cultures were treated with PTX (8 mM) or ADR (1 μM) or their combination (PTX + ADR), 24 hours later the cells were harvested and senescence was determined by histochemistry using the BioVision senescence detection kit. The results represent the percentage of SA-β-gal positive cells and represent the mean ± standard deviation of three independent experiments carrier out in triplicate. Statistical analysis Student "t" test. (*) p < 0.001 vs untreated control cells (CT). (•) p < 0.001 vs ADR.

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