MiRNAs modulated by fludarabine. Cluster analysis of 17 CLL patients based on 37 miRNAs differentially expressed pre and post fludarabine treatment. Statistical analysis revealed that 37 miRNAs are modulated by the drug both in sensitive (CR) and refractory (NR) patients. The expression values of the genes represented on the heatmap correspond to the values normalized on miRNA mean expression across all samples. CLL pre treatment are colored in blue, post treatment in red.