Figure 2
From: MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia
Classification of CLL patients in accordance to miRNAs that differentiate fludarabine responders from not responders. A) Eleven miRNAs are significantly (p < 0.05) modulated before fludarabine treatment between resistant and sensitive CLLs and were used for sample classification; cluster analysis revealed a good separation between the two classes. (B) Expression profile after fludarabine treatment; Ten miRNAs are differentially expressed (p < 0.05) in patients that will respond or not to chemotherapy; again, a good separation was achieved.