Figure 1From: HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signalingValidation of HOXB13-specific antibodies in prostate cancers: Expression of HOXB13 in various PCa cells by Western blot analysis (A) and immunocytochemistry (B). While LNCaP and MDA PCa 2b cells were HOXB13-retained cells, PC3 and DU145 cells were HOXB13-deficient cells. HOXB13 was immunostained in prostates with normal or tumor tissue with routine hematoxyline-eosin staining. Arrows indicate HOXB13 localized to the nucleus of luminal epithelial cells or cancer cells.Back to article page