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Table 6 Correlation between PN expression level and clinicopathological parameters.

From: Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker

Variable n PN expression (%) Univariate analysis Multivariate analysis  
   Low High P HR P
Age in years     0.575   
≤ 57 26 10 (38.5) 16 (61.5)   1  
>57 26 12 (46.2) 14 (53.8)   0.899 0.870
Sex     0.375   
Female 20 10 (50.0) 10 (50.0)   1  
Male 32 12 (37.5) 20 (62.5)   1.638 0.452
Histological type     0.083   
Well-differentiated 21 8 (38.1) 13 (61.9)   1  
Moderately-differentiated 8 1 (12.5) 7 (87.5)   3.720 0.271
Poorly-differentiated 8 6 (75.0) 2 (25.0)   0.184 0.86
Papillary 15 7 (46.7) 8 (53.3)   0.611 0.505
Tumor size (cm)     0.123   
≤ 5 29 15 (51.7) 14 (48.3)   1  
>5 23 7 (30.4) 16 (69.6)   2.493 0.161
Lymph node metastasis     0.830   
Absence 37 16 (43.2) 21 (56.8)   1  
Presence 15 6 (40.0) 9 (60.0)   1.459 0.590