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Table 1 HIF-1α target genes upregulated in response to hypoxia in GL261 control cells

From: Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

Affymetrix ID Gene Symbol Gene Title Fold Difference SD
1422470_at Bnip3 BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3 7.83 ± 2.26
1452094_at P4ha1 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide 3.46 ± 0.60
1421830_at Ak3l1 Adenylate kinase 3-like 1 3.09 ± 0.58
1418025_at Bhlhe40 Basic helix-loop-helix family, member e40 2.54 ± 0.04
1426599_a_at Slc2a1 Solute carrier family 2 (facilitated glucose transporter), member 1 2.24 ± 0.03
1420909_at Vegfa Vascular endothelial growth factor A 2.19 ± 0.48
1422612_at Hk2 Hexokinase 2 2.08 ± 0.20
1416488_at Ccng2 Cyclin G2 2.05 ± 0.60
1417149_at P4ha2 Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide 2.05 ± 0.12
  1. List of HIF-1α target genes found in the gene expression profile experiment as upregulated in response to hypoxia in GL261 control cells. For each gene the Affymetrix ID, the gene symbol, gene title, average fold difference and standard deviation (n = 2) are shown.