Figure 1
From: Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors
SPARC peptides FSEN and FSEC. SPARC peptides FSEN and FSEC were designed to correspond to the N-terminal and C-terminal loops of peptide FS-E, respectively. The native cysteine linkage was preserved in peptide FSEN; the unpaired cysteine was replaced with alanine. To maintain the conformation of peptide FSEC, cysteine 4 was linked with cysteine 3 instead of cysteine 2.