Figure 11From: Constitutively overexpressed 21 kDa protein in Hodgkin lymphoma and aggressive non-Hodgkin lymphomas identified as cytochrome B5b (CYB5B)Immunohistochemical detection of CYB5B protein in HL clinical biopsies. An example of intense (3+) positivity for CYB5B on the cell membrane (black arrow) and Golgi (red arrowhead) regions of Reed-Sternberg cells and mononuclear variants. Note speckled cytoplasmic staining pattern (green arrowhead). Magnification × 600.Back to article page