Figure 4
From: Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy
Bystander effect of gemcitabine in glioblastoma and osteosarcoma cell lines. A. Experimental design of the bystander effect assay: B. Bystander effect of gemcitabine with (blue bars) or without AGA (red bars). Data are the means ± S.D. of five replicates of at least three separate experiments. Statistical significance between untreated and AGA-treated cells was evaluated by a Student t-test (*, p < 0.05; **, p < 0.01): C. Absence of cisplatine and temozolomide bystander effect in SKI-1 and MNNG/HOS, respectively.