Table 1 Functional comparison of hepatoma and regeneration in young and old
Molecular and Cellular Functions | Significance | Number of genes1 | (%) |
|---|---|---|---|
Hepatoma in Young | Â | Â | Â |
Cancer | 2.1 × 10-3 - 4.9 × 10-2 | 12 | 33.3 |
Cellular Development | 4.6 × 10-3 - 4.9 × 10-2 | 8 | 22.2 |
Immune Response | 2.5 × 10-5 - 4.5 × 10-2 | 7 | 19.4 |
Skeletal and Muscular System Development and Function | 9.1 × 10-4 - 4.5 × 10-2 | 7 | 19.4 |
Cell Morphology | 4.6 × 10-3 - 4.9 × 10-2 | 7 | 19.4 |
Nervous System Development and Function | 4.6 × 10-3 - 4.9 × 10-2 | 6 | 16.7 |
Hair and Skin Development and Function | 2.1 × 10-5 - 1.4 × 10-2 | 4 | 11.1 |
Cell Cycle | 8.6 × 10-5 - 4.8 × 10-2 | 4 | 11.1 |
Cellular Function and Maintenance | 2.1 × 10-4 - 4.5 × 10-2 | 4 | 11.1 |
Amino Acid Metabolism | 4.6 × 10-3 - 4.9 × 10-2 | 3 | 8.3 |
Cell Death | 4.6 × 10-3 - 4.9 × 10-2 | 3 | 8.3 |
Hepatoma in Old | Â | Â | Â |
Cancer | 3.6 × 10-3 - 4.8 × 10-2 | 15 | 46.9 |
Cellular Movement | 2.3 × 10-3 - 4.8 × 10-2 | 13 | 40.6 |
Cell-to-Cell Signaling and Interaction | 4.9 × 10-3 - 4.8 10-2 | 10 | 31.3 |
Tissue Development | 4.7 × 10-3 - 3.9 × 10-2 | 9 | 28.1 |
Cell Morphology | 4.9 × 10-3 - 4.9 × 10-2 | 9 | 28.1 |
Organ Development | 3.1 × 10-3 - 4.8 × 10-2 | 6 | 18.8 |
Embryonic Development | 3.4 × 10-3 - 4.7 × 10-2 | 5 | 15.6 |
Organ Morphology | 3.1 × 10-3 - 3.4 × 10-2 | 4 | 12.5 |
Cell Death | 4.9 × 10-3 - 3.9 × 10-2 | 4 | 12.5 |
Skeletal and Muscular System Development and Function | 4.7 × 10-3 - 1.9 × 10-2 | 3 | 9.4 |
Amino Acid Metabolism | 4.9 × 10-3 - 4.3 × 10-2 | 2 | 6.3 |
Regenerated in Young | Â | Â | Â |
Cellular Growth and Proliferation | 1.6 × 10-3 - 4.8 × 10-2 | 5 | 38.5 |
Skeletal and Muscular System Development and Function | 1.6 × 10-3 - 3.7 × 10-2 | 5 | 38.5 |
Cell Morphology | 1.6 × 10-3 - 4.9 × 10-2 | 4 | 30.8 |
Cellular Assembly and Organization | 1.6 × 10-3 - 4.9 × 10-2 | 4 | 30.8 |
Cell-to-Cell Signaling and Interaction | 1.6 × 10-3 - 4.9 × 10-2 | 4 | 30.8 |
Small Molecule Biochemistry | 1.6 × 10-3 - 4.7 × 10-2 | 4 | 30.8 |
Tissue Development | 1.9 × 10-3 - 4.8 × 10-2 | 4 | 30.8 |
Cellular Development | 1.6 × 10-3 - 4.9 × 10-2 | 3 | 23.1 |
Cell cycle | 1.4 × 10-3 - 5.0 × 10-2 | 3 | 23.1 |
Amino Acid Metabolism | 1.6 × 10-3 - 4.6 × 10-2 | 2 | 15.4 |
Cellular Function and Maintenance | 1.6 × 10-3 - 3.2 × 10-2 | 2 | 15.4 |
Nervous System Development and Function | 1.6 × 10-3 - 4.8 × 10-2 | 2 | 15.4 |
Regenerated in Old | Â | Â | Â |
Nervous System Development and Function | 4.2 × 10-5 - 4.2 × 10-2 | 22 | 37.9 |
Molecular Transport | 3.8 × 10-3 - 4.2 × 10-2 | 19 | 32.8 |
Cell Morphology | 1.3 × 10-4 - 3.8 × 10-2 | 15 | 25.9 |
Small Molecule Biochemistry | 1.1 × 10-3 - 4.2 × 10-2 | 15 | 25.9 |
Cellular Movement | 1.5 × 10-3 - 4.2 × 10-2 | 15 | 25.9 |
Cell Signaling | 7.1 × 10-3 - 2.3 × 10-2 | 15 | 25.9 |
Cell-to-Cell Signaling and Interaction | 7.1 × 10-3 - 3.9 × 10-2 | 12 | 20.7 |
Tissue Morphology | 2.3 × 10-4 - 4.2 × 10-2 | 11 | 19.0 |
Lipid Metabolism | 1.1 × 10-3 - 3.8 × 10-2 | 10 | 17.2 |
Cellular Growth and Proliferation | 3.2 × 10-3 - 3.7 × 10-2 | 10 | 17.2 |
Skeletal and Muscular System Development and Function | 3.2 × 10-3 - 3.7 × 10-2 | 9 | 15.5 |
Cellular Assembly and Organization | 7.1 × 10-3 - 4.1 × 10-2 | 8 | 13.8 |
Cellular Function and Maintenance | 7.1 × 10-3 - 3.5 × 10-2 | 7 | 12.1 |
Cellular Development | 1.9 × 10-4 - 3.7 × 10-2 | 5 | 8.6 |