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Figure 2 | Molecular Cancer

Figure 2

From: RETRACTED ARTICLE: Loss of PDEF, a prostate-derived Ets factor is associated with aggressive phenotype of prostate cancer: Regulation of MMP 9 by PDEF

Figure 2

Effect of re-introduction of PDEF on directional migration, trans-well migration and anchorage independent growth in prostate cancer cells. A, Migration of PC3 cells expressing PDEF or PDEF T50A through Transwell membranes as described in Materials and Methods. B, PDEF overexpression decreases directional cell migration (in vitro wound healing migration of these cells). C, Representative photomicrographs from experiments testing colony formation as described in Materials and Methods. D, 3H-thymidine incorporation in PC3 PDEF overexpressing cells measured as described in Materials and Methods. E, Relative expression level of PDEF in these cell lines. Asterisks indicate significance levels of p < 0.05 with respect to controls.

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