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Figure 1 | Molecular Cancer

Figure 1

From: Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-β signaling

Figure 1

Characterization of the UOK257 cell lines. (A) FLCN protein expression in the UOK257 cell lines restored with wildtype or mutant FLCN. P, parental; HR, FLCN (H255R) mutant; 2, 3, 4 and 6, wildtype FLCN. (B) FLCN mRNA level was measured by quantitative RT-PCR. Columns, mean; bars, +SD (n = 3). (C) Cell growth of the UOK257 cell lines in vitro. Points, mean (n = 4). (D) Colony formation assay of the UOK257 cell lines and control HT1080 cell line in soft-agar culture. Columns, mean; bars, +SD (n = 3).

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