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Figure 1 | Molecular Cancer

Figure 1

From: Silencing of TESTIN by dense biallelic promoter methylation is the most common molecular event in childhood acute lymphoblastic leukaemia

Figure 1

Methylation plots for ALL bone marrow and normal PBL DNA. Bisulfite sequencing of ALL marrow, remission marrow and normal PBL samples; each horizontal grouping indicates one sequenced clone, individual circles represent each CpG site (open circles and closed circles represent unmethylated and methylated CpG sites respectively). A. Methylation plots of ALL samples initially assayed by MS-MLPA. B. Normal PBL DNA methylation plots. C. Further ALL methylation plots. D. Matched ALL and remission methylation plots. Dotted line indicates location of HhaI site used in MS-MLPA. Percent methylation is shown in parentheses.

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Molecular Cancer

ISSN: 1476-4598