Table 2 Frequencies of hsa-miR-124 methylation detected by qMSP analysis
From: Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer
methylation positivity (%) | Combined (and/or) methylation positivity (%) | ||||||
|---|---|---|---|---|---|---|---|
hsa-miR-124-1 | hsa-miR-124-2 | hsa-miR-124-3 | hsa-miR-124-1/-2/-3 | hsa-miR-124-1/-2 | hsa-miR-124-1/-3 | hsa-miR-124-2/-3 | |
Normal (n = 18) | 0.0 | 0.0 | 5.6 | 5.6 | 0.0 | 5.6 | 5.6 |
CIN1 (n = 36) | 27.8 | 5.6 | 11.1 | 30.6 | 30.6 | 27.8 | 13.9 |
CIN3 (n = 41) | 46.3 | 19.5 | 9.8 | 58.5 | 58.5 | 48.8 | 26.8 |
SCC (n = 29) | 86.2 | 82.8 | 72.4 | 93.1 | 93.1 | 89.7 | 86.2 |
AdCA (n = 15) | 93.3 | 80.0 | 73.3 | 100.0 | 93.3 | 100.0 | 93.3 |
normal cytology without CIN (n = 22) | 4.5 | 0.0 | 4.5 | 9.1 | 4.5 | 9.1 | 4.5 |
abnormal cytology with CIN3 (n = 21) | 47.6 | 47.6 | 23.8 | 71.4 | 71.4 | 57.1 | 47.6 |